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Aspirin + Paracetamol + Caffeine (headache powders)

SACAA Part 67 assessment

Generally acceptable for flying

Active ingredient(s)

Aspirin + Paracetamol + Caffeine (headache powders)

Simple compound analgesic

Guidance notes

Grand-Pa headache powders contain aspirin, paracetamol and caffeine only — no codeine and no other opioid. All three are non-sedating and generally acceptable for aviation duties at normal doses. Note aspirin's antiplatelet/bleeding effect on chronic use, and that caffeine may affect sleep quality. The underlying reason for repeated headache use remains the main aeromedical concern and frequent analgesic use should be discussed with a DAME.

Category rules that also apply

Controlled / narcotic substance — absolute prohibition

Narcotics, opioids, sedatives of dependence and stimulants of abuse (Schedule 5 and 6 medicines, and all illicit substances) are incompatible with aviation duty. No flying, air traffic control or cabin crew duty while the substance is being used, and return to duty requires formal DAME assessment of the medicine, the underlying condition and any dependence risk — not simply a washout period. These substances also trigger positive results on SACAA and operator substance screening, which carries licensing consequences separate from the medical assessment. Never combine them with alcohol.

Known SA brand names

Grand-PaGrandpaGrand-Pa Headache PowdersCompralDisprin ExtraPanado Extra

Our DAME partners

SACAA certified DAME list

Possible acceptable alternatives (same therapeutic group)

Alternatives are informational only. The underlying medical condition must also be assessed by a DAME — a condition can ground you even when the medicine is acceptable.

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SACAA Aviation Medicine (official reference)