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Aspirin + Paracetamol + Caffeine (headache powders)
SACAA Part 67 assessment
Generally acceptable for flying
Active ingredient(s)
Aspirin + Paracetamol + Caffeine (headache powders)
Simple compound analgesic
Guidance notes
Grand-Pa headache powders contain aspirin, paracetamol and caffeine only — no codeine and no other opioid. All three are non-sedating and generally acceptable for aviation duties at normal doses. Note aspirin's antiplatelet/bleeding effect on chronic use, and that caffeine may affect sleep quality. The underlying reason for repeated headache use remains the main aeromedical concern and frequent analgesic use should be discussed with a DAME.
Category rules that also apply
Controlled / narcotic substance — absolute prohibition
Narcotics, opioids, sedatives of dependence and stimulants of abuse (Schedule 5 and 6 medicines, and all illicit substances) are incompatible with aviation duty. No flying, air traffic control or cabin crew duty while the substance is being used, and return to duty requires formal DAME assessment of the medicine, the underlying condition and any dependence risk — not simply a washout period. These substances also trigger positive results on SACAA and operator substance screening, which carries licensing consequences separate from the medical assessment. Never combine them with alcohol.
Known SA brand names
Our DAME partners
Dr Berlize du Plessis
Senior DAME · MS213
Kenridge, Cape Town
Dr Brandon Head
Senior DAME · MS229
Sunninghill, Sandton
Dr Ernest Schutz
Senior DAME · MS028
Germiston
Dr Mariska van Tonder
Senior DAME · MS222
Somerset West
Dr Richard Albrecht
Senior DAME · MS074
Strubensvalley, Roodepoort
Dr. Schalk Reyneke
Senior DAME · MS123
Honeydew, Roodepoort
Possible acceptable alternatives (same therapeutic group)
- Paracetamol (Acetaminophen)Panado, Panamor, DolorolAcceptable
- IbuprofenBrufen, Nurofen, IbumaxAcceptable
Alternatives are informational only. The underlying medical condition must also be assessed by a DAME — a condition can ground you even when the medicine is acceptable.