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SACAA Part 67 medication guidance · unofficial

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GLP-1 agonists (semaglutide, liraglutide)

Part of group: Weight-loss agent

SACAA Part 67 assessment

Acceptable with conditions / grounding period

Active ingredient(s)

4 in group
GLP-1 agonists (semaglutide, liraglutide)SibutraminePhentermineOrlistat

Weight-loss agent

Stabilisation period

At least 2 weeks on a stable dose with no side effects

Guidance notes

Stimulant appetite suppressants (phentermine, sibutramine) are unacceptable — they raise heart rate and blood pressure and disturb sleep. Orlistat and GLP-1 agonists may be acceptable once side effects (hypoglycaemia risk, nausea, dehydration) have settled, with DAME approval and a stable dose.

Known SA brand names

DuromineXenicalOzempicSaxendaWegovyReductil

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SACAA Aviation Medicine (official reference)