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Mefloquine

SACAA Part 67 assessment

Not acceptable / incompatible with flying duties

Active ingredient(s)

Mefloquine

Antimalarial prophylaxis

Typical grounding period: 4 weeks

Measured from the last dose, and only once completely side-effect free.

Guidance notes

Table A1: unacceptable due to neuropsychiatric side effects. Must be discontinued at least 4 weeks before consideration, no history of symptoms is permitted, and SACAA/DAME must be contacted.

Known SA brand names

LariamMefliam

Our DAME partners

SACAA certified DAME list

Possible acceptable alternatives (same therapeutic group)

Alternatives are informational only. The underlying medical condition must also be assessed by a DAME — a condition can ground you even when the medicine is acceptable.

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SACAA Aviation Medicine (official reference)