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Mefloquine
SACAA Part 67 assessment
Not acceptable / incompatible with flying duties
Active ingredient(s)
Mefloquine
Antimalarial prophylaxis
Typical grounding period: 4 weeks
Measured from the last dose, and only once completely side-effect free.
Guidance notes
Table A1: unacceptable due to neuropsychiatric side effects. Must be discontinued at least 4 weeks before consideration, no history of symptoms is permitted, and SACAA/DAME must be contacted.
Known SA brand names
Contact a professional
Our partner Buchner Med can assist with aviation medical assessments and DAME consultations. Alternatively, find an SACAA-certified DAME directly through the official list.
Possible acceptable alternatives (same therapeutic group)
- Atovaquone + ProguanilMalanil, MalaroneConditional
- DoxycyclineDoxymycin, Cyclidox, VibramycinConditional
Alternatives are informational only. The underlying medical condition must also be assessed by a DAME — a condition can ground you even when the medicine is acceptable.