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SACAA Part 67 medication guidance · unofficial

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Methadone

Part of group: Controlled substance — opioid dependence treatment

SACAA Part 67 assessment

Not acceptable / incompatible with flying duties

Active ingredient(s)

3 in group
MethadoneBuprenorphineNaltrexone (opioid substitution)

Controlled substance — opioid dependence treatment

Typical grounding period: 72 hours (3 days)

Driven by Oxycodone / Hydrocodone / Pethidine / Fentanyl / Buprenorphine / Dihydrocodeine / Tilidine / Tapentadol.

Measured from the last dose, and only once completely side-effect free.

Guidance notes

Opioid substitution therapy is a Schedule 5/6 controlled substance treatment and is not compatible with any aviation duty. Both the medication and the underlying dependence disorder are disqualifying, and return to duty requires a formal DAME and aeromedical committee assessment with documented abstinence and monitoring.

Category rules that also apply

Controlled / narcotic substance — absolute prohibition

Narcotics, opioids, sedatives of dependence and stimulants of abuse (Schedule 5 and 6 medicines, and all illicit substances) are incompatible with aviation duty. No flying, air traffic control or cabin crew duty while the substance is being used, and return to duty requires formal DAME assessment of the medicine, the underlying condition and any dependence risk — not simply a washout period. These substances also trigger positive results on SACAA and operator substance screening, which carries licensing consequences separate from the medical assessment. Never combine them with alcohol.

Known SA brand names

MethadoneSubutexSuboxoneEspranorRevia

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SACAA Aviation Medicine (official reference)