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Misoprostol

SACAA Part 67 assessment

Not acceptable / incompatible with flying duties

Active ingredient(s)

Misoprostol

Cytoprotective agent

Guidance notes

Unacceptable for aviation duty. Commonly causes diarrhoea and abdominal cramping. Discuss a proton pump inhibitor with your DAME instead.

Known SA brand names

MisoprostolCytotec

Our DAME partners

SACAA certified DAME list

Possible acceptable alternatives (same therapeutic group)

Alternatives are informational only. The underlying medical condition must also be assessed by a DAME — a condition can ground you even when the medicine is acceptable.

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SACAA Aviation Medicine (official reference)