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Mucolytics and expectorants (Carbocisteine, Acetylcysteine, Bromhexine, Guaifenesin)

SACAA Part 67 assessment

Acceptable with conditions / grounding period

Alcohol plus a sedating medicine — additive effect

Alcohol multiplies the sedation and reaction-time impairment of this medicine. The two clocks run separately: the 8-hour alcohol restriction (and the 0.02 g/100 ml limit) and the medicine's own washout period — you are only clear once the later of the two has passed and you are completely side-effect free.

Contains alcohol or may contain alcohol

No aviation duty within 8 hours of any alcohol — and never above 0.02 g/100 ml blood alcohol concentration.

Many liquid medicines (cough mixtures, elixirs, tinctures, tonics, some drops and mouthwashes) contain ethanol as a solvent, and the label may only say 'ethanol', 'alcohol' or 'spiritus'. No aviation duty within 8 hours of consuming any alcohol, and never with a blood alcohol concentration of 0.02 g/100 ml or higher (CAR 91.02.3 / Part 67). Alcohol also multiplies the sedating effect of antihistamines, benzodiazepines, opioids and Z-drugs. Choose an alcohol-free preparation whenever one exists, and check the label of every liquid medicine before duty.

Active ingredient(s)

Mucolytics and expectorants (Carbocisteine, Acetylcysteine, Bromhexine, Guaifenesin)

Mucolytic / expectorant

Typical grounding period: 8 hours

Driven by Alcohol / ethanol-containing preparations.

Measured from the last dose, and only once completely side-effect free.

Guidance notes

Preparations containing only carbocisteine, guaifenesin or acetylcysteine without an alcohol base are acceptable. Check the label carefully — many cough syrups add alcohol, codeine, dextromethorphan, promethazine or pseudoephedrine, all of which are unacceptable.

Known SA brand names

CarbocisteineSolmucolAcetylcysteineACC 200BromhexineBisolvonGuaifenesinBenylin Wet Cough (alcohol-free)

Our DAME partners

SACAA certified DAME list

Possible acceptable alternatives (same therapeutic group)

Alternatives are informational only. The underlying medical condition must also be assessed by a DAME — a condition can ground you even when the medicine is acceptable.

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SACAA Aviation Medicine (official reference)