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Pregabalin
SACAA Part 67 assessment
Not acceptable / incompatible with flying duties
Active ingredient(s)
4 in groupAnti-epileptic
Stabilisation period
Minimum 3-month stabilisation period before any consideration.
Licence-class restriction
Unacceptable for pilots and ATC; may be considered case-by-case for cabin crew.
Guidance notes
Table A1: anti-epileptics (including gabapentin) are unacceptable for pilots and ATC. They may be considered for cabin crew case-by-case after a 3-month stabilisation period. The underlying seizure disorder is separately disqualifying.
Category rules that also apply
Controlled / narcotic substance — absolute prohibition
Narcotics, opioids, sedatives of dependence and stimulants of abuse (Schedule 5 and 6 medicines, and all illicit substances) are incompatible with aviation duty. No flying, air traffic control or cabin crew duty while the substance is being used, and return to duty requires formal DAME assessment of the medicine, the underlying condition and any dependence risk — not simply a washout period. These substances also trigger positive results on SACAA and operator substance screening, which carries licensing consequences separate from the medical assessment. Never combine them with alcohol.
Known SA brand names
Our DAME partners
Dr Berlize du Plessis
Senior DAME · MS213
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Dr Mariska van Tonder
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Dr Richard Albrecht
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Dr. Schalk Reyneke
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Honeydew, Roodepoort