Sulfasalazine, Mesalazine (5-aminosalicylic acid)

Sulfasalazine, Mesalazine (5-aminosalicylic acid)

Anti-inflammatory agent for bowel disease

Guidance notes

Case-by-case presentation. Enteric-coated sulfasalazine may be used with 6-monthly ophthalmology reporting plus FBC, U&E and urinalysis; 5-ASA derivatives such as mesalazine are preferred because sulfapyridine metabolites cause agranulocytosis and hypospermia. The inflammatory bowel disease itself must be stable.

Known SA brand names